My backside irritation continues. Food and Drug Administration has approved botulinum toxin A for treatment of strabismus, blepharospasm, and hemifacial spasm. Anal fissures are caused by injury trauma to the anal canal. He pulled my buttock apart and said oh my you have two large fissures. Topical nitroglycerin increases local blood flow and reduces pressure in the internal anal sphincter, which may further facilitate healing.
To the Editor: Myenteric nerves innervating the internal sphincter muscle of the anus produce and release nitric oxide,1,2 the chemical messenger that mediates. Application of a % nitroglycerin ointment may help heal a long-term (chronic) tear,or fissure,in the anus. You rub a pea-sized dot of cream on the fissure twice a day. An anal fissure, fissure in Ano or rectal fissure is a break or tear in the skin of the anal canal. Anal fissures may be noticed by bright red anal bleeding on toilet.